This article provides a summary of a retrospective study on global trends of female-specific cancers from 1990 to 2021. These cancers, which include breast, cervical, ovarian, and uterine cancers, make up nearly 40% of all cancers in women. The data for this study was based on the Global Burden of Disease Study 2021 (GBD 2021). This data was used to assess the global incidence, mortality, and disability-adjusted life years (DALYs) related to female-specific cancers. Age-standardized rates were used for regional comparisons and correlations between cancer burdens and economic levels were also assessed using the socio-demographic index (SDI).

The study found that in 2021, breast cancer had 2.08 million incident cases, 0.66 million deaths, and 20.25 million DALYs. Cervical, ovarian, and uterine cancers had significantly lower numbers of incident cases. Risk factors for these cancers varied; for instance, breast cancer risk factors included dietary habits, high body-mass index (BMI), high fasting plasma glucose, alcohol, tobacco use, and lack of physical activity. The research team found a rise in the burden of female-specific cancers, with variations based on region and demographic.

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